NanoGen Synthetic Bone Regeneration Material from Orthogen, LLC

NanoGen is a proprietary product developed by Orthogen, LLC. Microcrystalline calcium sulfate is converted to grains of calcium sulfate (size range 200 to 900 nanometers), which are tightly compressed together to form granules in sizes ranging from 400 to 1000 microns. NanoGen undergoes controlled degradation over a period of 12 weeks as compared to 4 to 6 weeks for traditional calcium sulfate. As it degrades, it leads to the formation of calcium phosphate which is the main inorganic component of bone and which also serves as a stimulus for further bone regeneration. Osteoblasts attach to the calcium phosphate and deposit more bone in the defect. Because it is completely degradable, bone defects grafted with NanoGen are eventually completely replaced with regenerated vital bone.